STAFF PROFILE

Dr. Onile focused on global profiling of human genes and proteins using harmonising MULTI-OMICS approaches to detect the biomarkers of normal physiology as well as pathological states of organisms. By the use of combined molecular approach, factors responsible for specific and non-specific condition of different genetic variation can be established within studied population. His research focused on field and molecular epidemiology of infectious diseases (mostly Neglected Tropical Disease-NTDs such as Schistosomiasis, Toxoplasmosis, Onchocerciasis etc). It also involve discovering molecular biomarkers for purposes like disease diagnosis, prediction and identification of possible vaccine candidates, as well as to gain understanding into host-pathogen relationship. With the employment of advanced molecular approaches such as bio-computation (Bioinformatics tools), genotyping and quantitative proteomics using mass spectrometry, it will be achievable to monitor different study groups that represent stages in diseases progression, response to/effect of identified vaccines and biomarkers in disease diagnosis and treatment. Dr. Onile is also interested in establishing the relationship between chronic infection and associated pathologies, thereafter employ several non-invasive molecular methods to screen for genetic susceptibility to diseases, associated pathologies and also identify arrays of biomarkers for early diagnosis of the disease, using different bio-fluids like serum and urine of patients from NTDs endemic communities. Dr. Onile is a recipient of the America Society of Tropical Medicine and Hygiene travel Award in 2017 where he presented a paper titled “Quantitative proteomic analysis of the human urine for novel protein biomarkers for schistosomiasis and its pathologies using label-free mass spectrometry” at the society 66th Annual general meeting. He is also involved in a short term Short-Term Research Exchange program at the Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa in the year 2016. Dr. Onile has shared his experience as resource person in several bioinformatics workshop across universities in Nigeria.